人黑色素細胞是神經嵴衍生細胞,位于人的某些器官,如皮膚、眼睛、內耳和軟腦膜。黑色素細胞不能向這些器官的移動,可以解釋先天性皮膚白斑(斑駁病)跟虹膜異色(不同顏色并置)之間的關系以及Waardenburg綜合征的先天性耳聾。皮膚黑色素細胞合成并轉運黑色素到周圍的角質細胞,使皮膚有色素沉積以保護皮膚對抗陽光輻射。隨著新的細胞培養技術和改良的培養方法,在成功培養這類細胞在純種群時,發現了新型的黑色素細胞基因——msgl,它能編碼一種與色素沉著相關的核蛋白。
人表皮黑色素細胞(淺色素)提取于人表皮組織,一代凍存。每管含有細胞數>5x10^5cells/ml,此細胞通過Fibronectin和NGF-receptor(p75)免疫熒光染色驗證,經測試不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌。細胞可以達到15倍增。
推薦培養基:黑色素細胞培養基 (MeIM, Cat. #2201)
貨號
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2200
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產地
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美國
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縮寫
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HEM-l
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規格
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5 x 10^5 /1ml
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用途
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科研
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儲存
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液氮
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運輸
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干冰
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關鍵字
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人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l 人表皮黑色素細胞-淺色素 HEM-l
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公司簡介
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合肥星肽生物科技有限公司作為專業的ScienCell中國代理商,專業經營實驗室科研用原代細胞、原代細胞專用培養基、原代細胞無血清培養基、干細胞、干細胞培養基、干細胞無血清培養基的研究和開發。合肥星肽生物科技有限公司始終致力于為客戶提供可靠的研究材料以及方便快捷的服務,對購買項目的前期資料提供,中期合同保證,后期貨物跟蹤到*終售后的確保項目準確到位,都有相關專業人士進行維護,確保您在合肥合肥星肽生物科技有限公司公司獲得*上等服務!
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聯系方式
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何經理,合肥星肽生物科技有限公司,Tel:0551-63802898 400-8702-898,
E-mail:info@qingbio.com http://www.huangyuansheng.cn QQ:514713116
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1.) Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ."Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment." 2014 Jan;124(1):425-36. doi: 10.1172/JCI69404. Epub 2013 Dec 20.
2.) Yang J, Bill MA, Young GS, La Perle K, Landesman Y, Shacham S, Kauffman M, Senapedis W, Kashyap T, Saint-Martin JR, Kendra K, Lesinski GB. (2014) 'Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells.'
3.) Yang J, Bill MA, Young GS, La Perle K, Landesman Y, Shacham S, Kauffman M, Senapedis W, Kashyap T, Saint-Martin JR, Kendra K, Lesinski GB. (2014) "Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells." PloS one. 9: e102983.
4.) Li JL, Mazar J, Zhong C, Faulkner GJ, Govindarajan SS, Zhang Z,Dinger ME, Meredith G, Adams C, Zhang S, Mattick JS, Ray A, Perera RJ (2013) 'Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network.'
5.) Li JL, Mazar J, Zhong C, Faulkner GJ, Govindarajan SS, Zhang Z,Dinger ME, Meredith G, Adams C, Zhang S, Mattick JS, Ray A, Perera RJ (2013) "Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network." . 3.
6.) Mazar J, DeYoung K, Khaitan D, Meister E, Almodovar A, Goydos J, Ray A, Perera RJ. (2010) "The regulation of miRNA-211 expression and its role in melanoma cell invasiveness." PLoS One. 5: e13779.
7.) Savaraj N, You M, Wu C, Wangpaichitr M, Kuo MT, Feun LG. (2010) "Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma." Curr Mol Med. 10: 405-12.
8.) Doudican N, Rodriguez A, Osman I, Orlow SJ. (2008) "Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells." Mol Cancer Res. 6: 1308-15.
9.) Palmer MB, Majumder P, Green MR, Wade PA, Boss JM. (2007) "A 3' Enhancer Controls Snail Expression in Melanoma Cells." Cancer Res. 67: 6113-20.
10.) May KM, Vogt A, Bachas LG, Anderson KW. (2005) "Vascular endothelial growth factor as a biomarker for the early detection of cancer using a whole cell-based biosensor." Anal Bioanal Chem. 382: 1010-6.
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